About the Disease


Homozygous Familial Hypercholesterolemia (HoFH) is an uncommon genetic condition that is inherited from both sides of the family and leads to high levels of cholesterol in the blood. It is characterized by marked elevation of low density lipoprotein cholesterol (LDL-C), xanthomata and premature cardiovascular disease. Untreated, HoFH often causes heart disease in the early teen years and sometimes even in early childhood. The LDL-C (bad cholesterol) level of an untreated person with HoFH is over 4 times the normal level.

About our Patient Care

Our dedicated Care Team will work with the physician's office and insurance on a patient's behalf so that our patients have more time to focus on their treatment and quality of life. We are here to listen, provide 

counseling on treatment, including side-effect management, and assist with sourcing third-party financial assistance.

As part of treatment, we provide:

Dedicated Care Team


We provide prescribers and patients with a dedicated care team for each of our disease state programs. This includes a primary pharmacy contact, clinical education, side-effects management, scheduled refill calls, and a direct phone, fax and email address.

In-Home Patient- and Family-Centric Care


We administer a nationwide nursing network, allowing patients to pursue in-home treatment or receive training on self-administrated drugs. Our nurses are ideally positioned to establish a partnership with patients and their families in order to provide clinical education and coaching that strengthen the patient's capacity to achieve therapy goals.

Shipping and Coordination of Care


We provide free overnight delivery of medications and necessary medical supplies and manage the coordination of care between prescribers, sites of care, nurses and patients to ensure dispenses and drug delivery align with the date and location of service.

Financial Assistance

We successfully identify and assist enrolling patients into any and all manufacturer co-pay and foundation support programs in order to minimize a potential financial burden to patients given the high-cost of specialty medications.


24/7/365 Access to a Pharmacist


We provide prescribers and patients access to a pharmacist 24/7/365 to ensure patients are always cared for.

Kynamro (mipomersen)

Brand Name | Kynamro Manufacturer | Kastle Route of Administration | Subcutaneous injection Approved Indication | Patients with homozygous familial hypercholesterolemia (HoFH) Self-Administration | Yes, after training Product Website | www.kynamro.com

Supported Treatments


Partnering with Prescribers

Licensed prescribers can submit a completed enrollment form directly to our Admission team. We will begin the process and communicate with your office every step of the way.

Send Us A Script


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1107 Nicholas Boulevard

Elk Grove Village, IL 60007

Corporate:  1-847-734-7373

Pharmacy:  1-800-410-8575



MON - FRI 8:00 AM - 5:30PM
SAT 9:30 - 3:30



© 2019-2020 Orsini Pharmaceutical Services. All rights reserved.